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Brain Stem MRI Signal Abnormalities in CADASIL
Author(s) -
Hugues Chabriat,
Ridha Mrissa,
C.D.P. Levy,
Katayoun Vahedi,
H. Taillia,
M T Iba-Zizen,
Anne Joutel,
Elisabeth TournierLasserve,
M.G. Bousser
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.2.457
Subject(s) - cadasil , medicine , pons , pathology , midbrain , white matter , stem cell , magnetic resonance imaging , fluid attenuated inversion recovery , disease , central nervous system , neuroscience , leukoencephalopathy , anatomy , radiology , biology , genetics
We recently showed that the severity of MRI signal abnormalities increases with age in CADASIL, an arteriopathy due to mutations of notch 3 gene on chromosome 19. Previous results also suggest that the various hemispheric subcortical areas have a different vulnerability to ischemia in this disease. The distribution of the lesions at the brain stem level has not yet been reported.

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