Brain Stem MRI Signal Abnormalities in CADASIL
Author(s) -
Hugues Chabriat,
Ridha Mrissa,
C.D.P. Levy,
Katayoun Vahedi,
H. Taillia,
M T Iba-Zizen,
Anne Joutel,
Elisabeth TournierLasserve,
M.G. Bousser
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.2.457
Subject(s) - cadasil , medicine , pons , pathology , midbrain , white matter , stem cell , magnetic resonance imaging , fluid attenuated inversion recovery , disease , central nervous system , neuroscience , leukoencephalopathy , anatomy , radiology , biology , genetics
We recently showed that the severity of MRI signal abnormalities increases with age in CADASIL, an arteriopathy due to mutations of notch 3 gene on chromosome 19. Previous results also suggest that the various hemispheric subcortical areas have a different vulnerability to ischemia in this disease. The distribution of the lesions at the brain stem level has not yet been reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom