Reduction of Apurinic/Apyrimidinic Endonuclease Expression After Transient Global Cerebral Ischemia in Rats | Zendy

Makoto Kawase | Zendy; Miki Fujimura | Zendy; Yuiko MoritaFujimura | Zendy; Pak H. Chan | Zendy

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Reduction of Apurinic/Apyrimidinic Endonuclease Expression After Transient Global Cerebral Ischemia in Rats

Author(s) -

Makoto Kawase,

Miki Fujimura,

Yuiko MoritaFujimura,

Pak H. Chan

Publication year - 1999

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.30.2.441

Subject(s) - medicine , ischemia , ap site , dna (apurinic or apyrimidinic site) lyase , endonuclease , transient (computer programming) , reduction (mathematics) , neuroscience , dna , genetics , biology , geometry , mathematics , computer science , operating system

To clarify the relationship between apurinic/apyrimidinic endonuclease (APE/Ref-1), a multifunctional protein in the DNA base excision repair pathway, and delayed neuronal cell death associated with apoptosis, we examined the expression of APE/Ref-1 before and after transient global ischemia in rats.

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