Intrathecal Expression of Proteins Regulating Apoptosis in Acute Stroke | Zendy

E. Tarkowski | Zendy; Lars Rosengren | Zendy; Christian Blomstrand | Zendy; Camilla Steen Jensen | Zendy; Sven Ekholm | Zendy; A Tarkowski | Zendy

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Intrathecal Expression of Proteins Regulating Apoptosis in Acute Stroke

Author(s) -

E. Tarkowski,

Lars Rosengren,

Christian Blomstrand,

Camilla Steen Jensen,

Sven Ekholm,

A Tarkowski

Publication year - 1999

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.30.2.321

Subject(s) - medicine , stroke (engine) , proinflammatory cytokine , cerebrospinal fluid , apoptosis , tumor necrosis factor alpha , ischemia , programmed cell death , immunology , pathology , anesthesia , inflammation , mechanical engineering , biochemistry , chemistry , engineering

The neuronal death that accompanies an ischemic stroke has previously been attributed to a necrotic process. However, numerous studies in experimental models of ischemia have recently indicated that programmed cell death, also called apoptosis, may contribute to neuronal death. The aim of the present study was to investigate the intrathecal levels of proteins regulating apoptosis in acute stroke and to relate these levels to brain damage and to production of proinflammatory and anti-inflammatory cytokines.

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