Association of the Platelet Glycoprotein IIb HPA-3 Polymorphism With Survival After Acute Ischemic Stroke
Author(s) -
Angela M. Carter,
Andrew J. Catto,
John Bamford,
Peter J. Grant
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.12.2606
Subject(s) - medicine , ischemic stroke , platelet , platelet membrane glycoprotein , glycoprotein , stroke (engine) , polymorphism (computer science) , gastroenterology , cardiology , genotype , gene , ischemia , genetics , mechanical engineering , biology , engineering
The role of polymorphisms of the platelet glycoprotein (GP) IIb/IIIa receptor in the development of cardiovascular disease has been the subject of intensive research. The aim of this study was to determine the association of the HPA-3 polymorphism of platelet GPIIb with ischemic stroke and subsequent survival and to identify possible interactions of HPA-3 with classic risk factors.
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