Markers of Thrombin and Platelet Activity in Patients With Atrial Fibrillation | Zendy

William M. Feinberg | Zendy; Lesly A. Pearce | Zendy; Robert G. Hart | Zendy; Mary Cushman | Zendy; Elaine Cornell | Zendy; Gregory Y.H. Lip | Zendy; Edwin G. Bovill | Zendy

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Markers of Thrombin and Platelet Activity in Patients With Atrial Fibrillation

Author(s) -

William M. Feinberg,

Lesly A. Pearce,

Robert G. Hart,

Mary Cushman,

Elaine Cornell,

Gregory Y.H. Lip,

Edwin G. Bovill

Publication year - 1999

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.30.12.2547

Subject(s) - medicine , atrial fibrillation , stroke (engine) , cardiology , aspirin , antithrombotic , platelet activation , heart failure , fibrinogen , risk factor , thrombosis , embolism , platelet , mechanical engineering , engineering

Markers of thrombin generation and platelet activation are often elevated in patients with nonvalvular atrial fibrillation, but it is unclear whether such markers usefully predict stroke. Therefore, we undertook the present study to assess the relationship between prothrombin fragment F1.2 (F1.2), beta-thromboglobulin (BTG), fibrinogen, and the factor V Leiden mutation with stroke in atrial fibrillation.

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