Open AccessNeuroprotection for Acute Stroke
Author(s) -
Keith W. Muir,
Donald G. Grosset
Publication year - 1999
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.30.1.180
Subject(s) - medicine , neuroprotection , stroke (engine) , acute stroke , intensive care medicine , tissue plasminogen activator , mechanical engineering , engineering
With the exception of the National Institutes of Neurological Disorders and Stroke trial of recombinant tissue plasminogen activator, clinical trials in stroke have failed to show improved outcome. If further negative results such as those of recent large neuroprotective trials are to be avoided, trial methodology must be reevaluated.
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