Cerebral Anoxia: Protein Metabolism During Recovery in In Vitro Model | Zendy

Takehiko Yanagihara | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Cerebral Anoxia: Protein Metabolism During Recovery in In Vitro Model

Author(s) -

Takehiko Yanagihara

Publication year - 1972

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.3.6.733

Subject(s) - anoxic waters , in vitro , amino acid , metabolism , medicine , biochemistry , protein biosynthesis , anesthesia , biology , ecology

Amino acid incorporation into proteins of rabbit brain slices was studied during the recovery stage after various anoxic periods in an in vitro experimental model. There was a distinct difference between anoxic periods up to five minutes and those beyond ten minutes. In the former, inhibition of amino acid incorporation was of lesser degree and was reversible. On the other hand, more than 50% inhibition was observed following anoxic periods of 30 minutes and this inhibition was irreversible. Amino acid incorporation into proteins was more sensitive to anoxia than was amino acid transport into brain slices.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research