Cerebral Microangiography After Hypocarbia and Hypercarbia | Zendy

Timothy Harrington | Zendy; Giovanni Di Chiro | Zendy

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Cerebral Microangiography After Hypocarbia and Hypercarbia

Author(s) -

Timothy Harrington,

Giovanni Di Chiro

Publication year - 1972

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.3.5.553

Subject(s) - microangiography , medicine , hypercarbia , middle cerebral artery , cardiology , ischemia , anatomy , hypoxemia

Ischemic infarction was obtained in the basal ganglia and internal capsule of the Rhesus monkey by clipping the middle cerebral artery at its origin through a transorbital approach. The postmortem microvasculature was demonstrated using microtized barium (Micropaque) and soft x-ray technology. The effects on this microvasculature induced by antemortem variations in Paco2 in tne normal and the acutely infarcted animal were studied. Microangiography was shown to be useful in the study of dynamic vascular changes in the deep structures of the ischemic brain.

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