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Intracranial Pressure Gradients Associated With Experimental Cerebral Embolism
Author(s) -
Mário Brock,
J.Robert Beck,
E. Markakis,
H. Dietz
Publication year - 1972
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.3.2.123
Subject(s) - medicine , cerebral perfusion pressure , intracranial pressure , cats , cerebral blood flow , embolism , perfusion , cerebral circulation , anesthesia , blood pressure , pressure gradient , cardiology , physics , mechanics
In a series of 20 cats unilateral cerebral oil embolism was followed by the development of clinical signs of increased intracranial pressure. Simultaneous bilateral epidural pressure measurements revealed marked pressure gradients between both cerebral hemispheres. Such local (tissue) pressure gradients possibly influence local cerebral blood flow (mainly in the diseased areas) by means of alterations in local tissue perfusion pressure.

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