Open AccessMechanisms of Cerebrovascular Events as Assessed by Procoagulant Activity, Cerebral Microemboli, and Platelet Microparticles in Patients With Prosthetic Heart Valves
Author(s) -
Thomas Geiser,
Matthias Sturzenegger,
Urs Genewein,
André Haeberli,
Jürg H. Beer
Publication year - 1998
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.29.9.1770
Subject(s) - medicine , transcranial doppler , platelet , stroke (engine) , pathophysiology , platelet activation , coagulation , cardiology , aspirin , flow cytometry , platelet poor plasma , gastroenterology , anesthesia , surgery , pathology , platelet rich plasma , immunology , mechanical engineering , engineering
Cerebrovascular events (CVE) in patients with prosthetic heart valves (PHV) have remained a severe and frequent complication despite oral anticoagulation with or without aspirin. We studied the possible pathophysiological involvement of platelet-derived microparticles (PMP) as a contributing factor for the increased incidence of CVE in patients with PHV.
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