Open AccessAntioxidants Inhibit ATP-Sensitive Potassium Channels in Cerebral Arterioles
Author(s) -
Enoch P. Wei,
Hermes A. Kontos,
Joseph S. Beckman
Publication year - 1998
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.29.4.817
Subject(s) - medicine , potassium channel , potassium , stroke (engine) , arteriole , pharmacology , neuroscience , microcirculation , chemistry , organic chemistry , mechanical engineering , engineering , biology
Hydrogen peroxide and peroxynitrite are capable of generating hydroxyl radical and are commonly suspected as sources of this radical in tissues. It would be useful to distinguish the source of hydroxyl radical in pathophysiological conditions and to clarify the mechanisms by which antioxidants modify vascular actions of oxidants.
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