Duration of Neuroprotective Treatment for Ischemic Stroke | Zendy

Alexander Dyker | Zendy; K. R. Lees | Zendy

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Duration of Neuroprotective Treatment for Ischemic Stroke

Author(s) -

Alexander Dyker,

K. R. Lees

Publication year - 1998

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.29.2.535

Subject(s) - medicine , neuroprotection , stroke (engine) , ischemic stroke , duration (music) , ischemia , cardiology , mechanical engineering , engineering , art , literature

The therapeutic time window for thrombolysis appears to be extremely short, probably because of the hemorrhagic complications associated with late reperfusion of ischemic brain tissue. Other neuroprotective forms of treatment continue to be developed, although their efficacy has yet to be conclusively proved in patients. The duration of treatment in recent phase 3 trials ranges from a single bolus injection to 12 weeks of oral therapy.

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