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Subtractive Cloning Identifies Tissue Inhibitor of Matrix Metalloproteinase-1 (TIMP-1) Increased Gene Expression Following Focal Stroke
Author(s) -
Xinkang Wang,
Frank C. Barone,
Raymond F. White,
Giora Feuerstein
Publication year - 1998
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.29.2.516
Subject(s) - suppression subtractive hybridization , cdna library , complementary dna , medicine , gene expression , ischemia , stroke (engine) , microbiology and biotechnology , gene , pathology , biology , genetics , mechanical engineering , engineering
Differential gene expression has been reported following the onset of focal stroke. To identify de novo expression of ischemia-induced genes, we applied subtractive cDNA library strategy to identify the genes that are selectively upregulated by focal stroke.

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