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Control of Vascular Tone by Endogenous Endothelin-1 in Human Pial Arteries
Author(s) -
Éric Thorin,
Thanh-Dung Nguyen,
Alain Bouthillier
Publication year - 1998
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.29.1.175
Subject(s) - myograph , medicine , endocrinology , cerebral arteries , endothelin receptor , endothelin 1 , apamin , vasoconstriction , agonist , receptor antagonist , basilar artery , endothelium , tetraethylammonium , antagonist , receptor , potassium channel , chemistry , potassium , organic chemistry
Endothelin-1 (ET) has been shown to be involved in human pathological conditions, but its physiological function remains to be elucidated. The aim of this work was to assess whether endothelium-derived ET was involved in the overall responsiveness of freshly isolated human pial arteries.

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