Prediction of Impending Hemorrhagic Transformation in Ischemic Stroke Using Magnetic Resonance Imaging in Rats | Zendy

Robert A. Knight | Zendy; Peter B. Barker | Zendy; S. C. Fagan | Zendy; Y. Li | Zendy; Michael A. Jacobs | Zendy; K.M.A. Welch | Zendy

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Prediction of Impending Hemorrhagic Transformation in Ischemic Stroke Using Magnetic Resonance Imaging in Rats

Author(s) -

Robert A. Knight,

Peter B. Barker,

S. C. Fagan,

Y. Li,

Michael A. Jacobs,

K.M.A. Welch

Publication year - 1998

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.29.1.144

Subject(s) - medicine , magnetic resonance imaging , ischemia , petechial rash , stroke (engine) , occlusion , thrombolysis , middle cerebral artery , reperfusion injury , anesthesia , nuclear medicine , radiology , pathology , surgery , mechanical engineering , myocardial infarction , engineering

Hemorrhagic transformation (HT) of ischemic brain tissue may occur in stroke patients either spontaneously or after thrombolysis. A method to assess the risk of HT in ischemic tissue after stroke would improve the safety of thrombolytic therapy. As a means of predicting HT, we investigated the role of contrast-enhanced MRI at acute time points in a rat middle cerebral artery occlusion model with reperfusion.

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