Cortical hypoperfusion after global forebrain ischemia in rats is not caused by microvascular leukocyte plugging. | Zendy

Ulrich Dirnagl | Zendy; K. Niwa | Zendy; G. Sixt | Zendy; Arno Villringer | Zendy

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Cortical hypoperfusion after global forebrain ischemia in rats is not caused by microvascular leukocyte plugging.

Author(s) -

Ulrich Dirnagl,

K. Niwa,

G. Sixt,

Arno Villringer

Publication year - 1994

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.25.5.1028

Subject(s) - ischemia , microcirculation , medicine , perfusion , laser doppler velocimetry , extravasation , cerebral cortex , cerebral blood flow , endothelium , cortex (anatomy) , brain ischemia , pathology , anesthesia , blood flow , neuroscience , biology

We tested the hypothesis that cerebral hypoperfusion after experimental global cerebral ischemia is caused by plugging of the microcirculation with activated leukocytes using in vivo microscopic observation of the behavior of leukocytes in the cortical microcirculation during the transition from postischemic hyperperfusion to hypoperfusion.

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