Calcium/calmodulin-dependent protein kinase II activity in focal ischemia with reperfusion in rats.
Author(s) -
Steven Hanson,
James C. Grotta,
M. Neal Waxham,
Jaroslaw Aronowski,
Peter T. Ostrow
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.2.466
Subject(s) - ischemia , medicine , calcium , calmodulin , endocrinology , kinase , cardiology , protein kinase a , biochemistry , biology
Evidence linking changes in calcium/calmodulin-dependent protein kinase II activity with ischemic cell death has been reported in animal models of global ischemia. The purpose of this study was to delineate the course of these changes after focal ischemia and to clarify the relation of changes in activity of calcium/calmodulin-dependent protein kinase II to the process of ischemic cell death.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom