Open AccessGamma irradiation inhibits neointimal hyperplasia in rats after arterial injury.
Author(s) -
Steven Shimotakahara,
Marc R. Mayberg
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.2.424
Subject(s) - medicine , neointimal hyperplasia , stroke (engine) , irradiation , cardiology , restenosis , stent , mechanical engineering , physics , nuclear physics , engineering
Restenosis complicates a significant proportion of endovascular and open vascular procedures such as carotid endarterectomy. In contrast to the primary atheroma, restenosis is characterized by intimal hyperplasia of vascular smooth muscle cells. We hypothesized that gamma radiation would reduce restenosis by limiting intimal hyperplasia after arterial injury.
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