Open AccessLeukocyte-induced acute endothelial dysfunction in middle cerebral artery in rabbits. Response to aggregating platelets.
Author(s) -
Sergey E. Akopov,
R. Sercombe,
Jacques Seylaz
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.11.2246
Subject(s) - medicine , dilator , sodium nitroprusside , cerebral arteries , acetylcholine , middle cerebral artery , platelet , endothelium , anesthesia , endocrinology , vasodilation , nitric oxide , ischemia
Recent evidence suggests a possible role for leukocytes in angiospastic reactions of large cerebral arteries. This study examined the effect of activation of endogenous circulating leukocytes on endothelium-dependent relaxation in the middle cerebral artery in rabbits.
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