Responses of cerebral arterioles to kainate.
Author(s) -
Frank M. Faraci,
Keith Breese,
Donald D. Heistad
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.10.2080
Subject(s) - kainate receptor , medicine , nitric oxide , glutamate receptor , vasodilation , cerebral arteries , anesthesia , endocrinology , pharmacology , receptor , ampa receptor
Neurons release nitric oxide in response to glutamate. Glutamate acts via activation of different receptor subtypes, including N-methyl-D-aspartate and kainate receptors. This study examined the hypothesis that kainate produces dilatation of cerebral arterioles that is dependent on the formation of nitric oxide.
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