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Reperfusion after thrombolytic therapy in ischemic stroke measured by single-photon emission computed tomography.
Author(s) -
Alison E. Baird,
Geoffrey A. Donnan,
M.C. Austin,
GJ Fitt,
Stephen M. Davis,
W. J. McKay
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.1.79
Subject(s) - streptokinase , medicine , perfusion , single photon emission computed tomography , perfusion scanning , emission computed tomography , stroke (engine) , cardiology , thrombolysis , reperfusion therapy , ischemia , spect imaging , nuclear medicine , myocardial infarction , mechanical engineering , engineering
We used 99mTc-hexamethylpropyleneamine oxime single-photon emission computed tomography (SPECT) to study cerebral perfusion in patients treated with streptokinase for acute ischemic stroke in an open and prospective study. Our primary aims were (1) to compare the extent of reperfusion between patients who had received thrombolytic therapy and a control group studied during the same period who were ineligible to receive such therapy and (2) to determine if, among all patients, reperfusion led to improved outcome.

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