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P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion.
Author(s) -
Yasushi Okada,
Brian R. Copeland,
Etsuro Mori,
M M Tung,
Winston S. Thomas,
Gregory J. del Zoppo
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.1.202
Subject(s) - ischemia , medicine , cell adhesion molecule , intercellular adhesion molecule 1 , selectin , e selectin , middle cerebral artery , endothelium , p selectin , reperfusion injury , brain ischemia , intracellular , adhesion , pathology , platelet , cell adhesion , microbiology and biotechnology , platelet activation , immunology , biology , chemistry , organic chemistry
Polymorphonuclear leukocytes have been implicated in the development of the "no-reflow" phenomenon after focal cerebral ischemia and reperfusion. To further understand the role of granulocytes in microvascular occlusions, the responses of the granulocyte-endothelial cell adhesion molecules P-selectin and intercellular adhesion molecule-1 during middle cerebral artery ischemia and reperfusion were examined in a primate model.

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