Impaired relaxation of the carotid artery during activation of ATP-sensitive potassium channels in atherosclerotic monkeys.
Author(s) -
Frank M. Faraci,
Kristen I. Orgren,
Donald D. Heistad
Publication year - 1994
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.25.1.178
Subject(s) - acetylcholine , medicine , sodium nitroprusside , endocrinology , glibenclamide , potassium channel , vasodilation , contraction (grammar) , cardiology , nitric oxide , diabetes mellitus
This study examined the hypotheses that (1) atherosclerosis impairs relaxation of the carotid artery in response to activation of adenosine triphosphate (ATP)-sensitive potassium channels and (2) regression of atherosclerosis restores the response toward normal.
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