Time course of variations in rabbit cerebrospinal fluid levels of calcitonin gene-related peptide- and substance P-like immunoreactivity in experimental subarachnoid hemorrhage. | Zendy

Yves R. Tran Dinh | Zendy; M. Berchíd Débdi | Zendy; J.Y. Couraud | Zendy; Christophe Crémi | Zendy; Jacques Seylaz | Zendy; R. Sercombe | Zendy

Open Access

Time course of variations in rabbit cerebrospinal fluid levels of calcitonin gene-related peptide- and substance P-like immunoreactivity in experimental subarachnoid hemorrhage.

Author(s) -

Yves R. Tran Dinh,

M. Berchíd Débdi,

J.Y. Couraud,

Christophe Crémi,

Jacques Seylaz,

R. Sercombe

Publication year - 1994

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.25.1.160

Subject(s) - medicine , cerebrospinal fluid , calcitonin gene related peptide , substance p , subarachnoid hemorrhage , neuropeptide , calcitonin , pathology , peptide , endocrinology , receptor , biochemistry , chemistry

Cerebral vasospasm after subarachnoid hemorrhage may result partially from the imbalance between vasodilator and vasoconstrictor factors. The vasodilator peptides substance P and calcitonin gene-related peptide contained in the trigeminovascular system are involved in the vasomotor phenomenon occurring after subarachnoid hemorrhage. The delayed arterial narrowing may reflect the time course of the release of these peptides. Therefore, we followed the time course of the changes in cerebrospinal fluid immunoreactivity of substance P and calcitonin gene-related peptide in a model of experimental subarachnoid hemorrhage.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research