Bilirubin levels in subarachnoid clot and effects on canine arterial smooth muscle cells. | Zendy

Greg Trost | Zendy; K Nagatani | Zendy; A B Goknur | Zendy; Robert A. Haworth | Zendy; Gerard B. Odell | Zendy; Thomas A. Duff | Zendy

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Bilirubin levels in subarachnoid clot and effects on canine arterial smooth muscle cells.

Author(s) -

Greg Trost,

K Nagatani,

A B Goknur,

Robert A. Haworth,

Gerard B. Odell,

Thomas A. Duff

Publication year - 1993

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.24.8.1241

Subject(s) - medicine , bilirubin , vasospasm , myocyte , vascular smooth muscle , contraction (grammar) , cerebral arteries , verapamil , vasodilation , endocrinology , subarachnoid hemorrhage , cardiology , calcium , smooth muscle

Previous studies have suggested that bilirubin is a potential contributor to cerebral vasospasm. The purpose of this investigation was to determine whether bilirubin accrues in subarachnoid clot, whether its vasoconstrictive effect could involve a direct action on arterial smooth muscle cells, and, if so, whether bilirubin affects their Ca2+ uptake.

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