Open AccessDexamethasone prevents cerebral infarction without affecting cerebral blood flow in neonatal rats.
Author(s) -
Ursula I. Tuor,
Carmine Simone,
John Barks,
Martin Post
Publication year - 1993
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.24.3.452
Subject(s) - medicine , dexamethasone , cerebral blood flow , cerebral infarction , anesthesia , stroke (engine) , ischemia , mechanical engineering , engineering
We recently demonstrated that pretreatment with the synthetic glucocorticoid dexamethasone prevents hypoxic-ischemic brain damage in neonatal rats. Presently, we examine whether this protective effect of dexamethasone is due to an improvement in local cerebral blood flow.
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