Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats. | Zendy

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Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats.

Author(s) -

Andrew Slivka

Publication year - 1993

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.24.2.241

Subject(s) - medicine , hydralazine , ischemia , stroke (engine) , blood pressure , spontaneously hypertensive rat , middle cerebral artery , cardiology , common carotid artery , anesthesia , carotid arteries , mechanical engineering , engineering

Antihypertensive treatment with hydralazine for 10 weeks but not 6 weeks reduces infarct size in 13-week-old spontaneously hypertensive rats subjected to focal cerebral ischemia. This study was designed to examine whether the duration of treatment needed to reduce infarct size depends on how long hypertension is present before the initiation of antihypertensive therapy.

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