Endothelial modulation of contractions caused by oxyhemoglobin and NG-nitro-L-arginine in isolated dog and monkey cerebral arteries.
Author(s) -
Noboru Toda,
Kazuhide Ayajiki,
Tomonori Okamura
Publication year - 1993
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.24.10.1584
Subject(s) - medicine , cerebral arteries , cardiology , arginine , endothelium , anatomy , biochemistry , chemistry , amino acid
Oxyhemoglobin is a key substance in provoking cerebral vasospasm and a scavenger of nitric oxide. The present study was designed to determine whether suppression of the action of endothelium-derived nitric oxide is involved in oxyhemoglobin-induced cerebroarterial contraction.
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