Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats. | Zendy

W. Dalton Dietrich | Zendy; Ofelia F. Alonso | Zendy; Raul Busto | Zendy

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Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats.

Author(s) -

W. Dalton Dietrich,

Ofelia F. Alonso,

Raul Busto

Publication year - 1993

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.24.1.111

Subject(s) - medicine , extravasation , ischemia , blood–brain barrier , anesthesia , thalamus , evans blue , hippocampus , cerebral cortex , brain ischemia , endocrinology , hypothermia , central nervous system , pathology , radiology

Clinical and experimental data indicate that hyperglycemia can aggravate the consequences of stroke and cerebral ischemia. The purpose of this study was to examine the effects of moderate hyperglycemia on the response of the blood-brain barrier to normothermic (37 degrees C) and hypothermic (30 degrees C) global forebrain ischemia.

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