Edema, cation content, and ATPase activity after middle cerebral artery occlusion in rats. | Zendy

GuoYuan Yang | Zendy; S F Chen | Zendy; Hiroyuki Kinouchi | Zendy; Pak H. Chan | Zendy; Philip R. Weinstein | Zendy

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Edema, cation content, and ATPase activity after middle cerebral artery occlusion in rats.

Author(s) -

GuoYuan Yang,

S F Chen,

Hiroyuki Kinouchi,

Pak H. Chan,

Philip R. Weinstein

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.9.1331

Subject(s) - medicine , occlusion , edema , anesthesia , ischemia , atpase , blood flow , cerebral edema , middle cerebral artery , endocrinology , biochemistry , chemistry , enzyme

Reduction of cerebral blood flow results in several acute metabolic disturbances, including a reduction in Na,K-ATPase activity. The relation between this reduction and the onset of edema is unknown, as is the effect of restoration of blood flow. Therefore, we investigated the role of decreased Na,K-ATPase activity in the pathogenesis and time course of ischemic brain edema and reperfusion.

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