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Increases in cerebral blood flow in rat hippocampus after medial septal injection of naloxone.
Author(s) -
Junichi Nishimura,
Yutaka Endo,
Fukuko Kimura
Publication year - 1992
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.23.9.1325
Subject(s) - medicine , (+) naloxone , hippocampus , hippocampal formation , cerebral blood flow , anesthesia , endocrinology , cannula , caudate nucleus , septal nuclei , opioid , surgery , receptor
In a previous study, we occasionally found that the rat given naloxone in the preoptic region develops behavioral seizures. In view of knowledge that the forebrain including the medial septal nucleus provides cholinergic projections to the hippocampal formation, the present study examined the effects of naloxone injected into the medial septal nucleus on the local blood flow in the hippocampus.

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