Distribution of the 72-kd heat-shock protein as a function of transient focal cerebral ischemia in rats.
Author(s) -
Y Li,
Michael Chopp,
Julio Herrero García,
Y Yoshida,
Z G Zhang,
Steven R. Levine
Publication year - 1992
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.23.9.1292
Subject(s) - heat shock protein , glial fibrillary acidic protein , medicine , ischemia , pathology , hsp70 , immunohistochemistry , h&e stain , shock (circulatory) , biology , biochemistry , gene
The significance and physiological implications of the expression of the 72-kd heat-shock protein in ischemic tissue are unknown. To enhance our understanding of the relation between ischemic cell damage and 72-kd heat-shock protein expression, we evaluated the cellular expression and the anatomic distribution of 72-kd heat-shock protein in conjunction with the morphological analysis of rat brain, as a function of the duration of a single arterial occlusion.
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