Increased plasma endothelin-1 in acute ischemic stroke. | Zendy

I. Ziv | Zendy; Gideon Fleminger | Zendy; Ruth Djaldetti | Zendy; Anat Achiron | Zendy; E. Melamed | Zendy; Mordechai Sokolovsky | Zendy

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Increased plasma endothelin-1 in acute ischemic stroke.

Author(s) -

I. Ziv,

Gideon Fleminger,

Ruth Djaldetti,

Anat Achiron,

E. Melamed,

Mordechai Sokolovsky

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.7.1014

Subject(s) - medicine , endothelins , endothelin receptor , endothelin 1 , pathogenesis , vasoconstriction , radioimmunoassay , stroke (engine) , cerebral infarction , endocrinology , cardiology , ischemia , mechanical engineering , receptor , engineering

Endothelins are a recently discovered group of most powerful vasoconstrictor peptides. Endothelin-1 is produced by endothelial cells, and endothelin-3 is derived from neuronal tissue. Theoretically, endothelin-mediated vasoconstriction may enhance ischemic neuronal damage. This study aimed to measure plasma levels of both endothelins in patients with acute nonhemorrhagic cerebral infarction.

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