Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats. | Zendy

Todd R. Ridenour | Zendy; David S. Warner | Zendy; Michael M. Todd | Zendy; A C McAllister | Zendy

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Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats.

Author(s) -

Todd R. Ridenour,

David S. Warner,

Michael M. Todd,

A C McAllister

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.5.733

Subject(s) - medicine , ischemia , hypothermia , occlusion , anesthesia , infarction , ligation , middle cerebral artery , cardiology , myocardial infarction

Mild hypothermia (32-35 degrees C) has been repeatedly shown in laboratory models to reduce damage resulting from global cerebral ischemic insults. Little information is available, however, regarding the protective potential of mild hypothermia against focal ischemia. We designed the present study to determine whether mild hypothermia influences outcome from either temporary or permanent middle cerebral artery occlusion in the rat.

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