Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis. | Zendy

Robert N. Willette | Zendy; Charles F. Sauermelch | Zendy; R Rycyna | Zendy; Sandip Sarkar | Zendy; G Feuerstein | Zendy; Andrew J. Nichols | Zendy; Eliot H. Ohlstein | Zendy

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Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis.

Author(s) -

Robert N. Willette,

Charles F. Sauermelch,

R Rycyna,

Sandip Sarkar,

G Feuerstein,

Andrew J. Nichols,

Eliot H. Ohlstein

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.5.703

Subject(s) - medicine , thrombosis , cardiology , aspirin , platelet , common carotid artery , anesthesia , ex vivo , thrombus , in vivo , carotid arteries , microbiology and biotechnology , biology

Platelet-fibrin thrombi in the lumen of atherostenotic carotid arteries may underlie transient ischemic attacks and cerebral infarction. For this reason, we investigated the antiplatelet and antithrombotic effects of a novel and potent platelet fibrinogen receptor (glycoprotein IIb/IIIa) antagonist (SK&F 106760).

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