Estimation of cerebrovascular reactivity using transcranial Doppler, including the use of breath-holding as the vasodilatory stimulus. | Zendy

Hugh S. Markus | Zendy; M J Harrison | Zendy

Open Access

Estimation of cerebrovascular reactivity using transcranial Doppler, including the use of breath-holding as the vasodilatory stimulus.

Author(s) -

Hugh S. Markus,

M J Harrison

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.5.668

Subject(s) - hypocapnia , medicine , hypercapnia , hyperventilation , vasodilation , anesthesia , transcranial doppler , carbon dioxide , breathing , cardiology , ecology , acidosis , biology

A proportion of individuals with carotid artery stenosis show a reduced cerebrovascular reserve as measured by a reduced cerebral arterial vasodilatory response to carbon dioxide. Two methods of quantifying this vasodilatory response, using transcranial Doppler ultrasonography, have been in general use: the total range of vasodilation between hypocapnia, induced by hyperventilation, and hypercapnia induced by breathing carbon dioxide, and the response to breathing a fixed concentration of 5% carbon dioxide. We studied whether it is possible to use the rise in carbon dioxide occurring during breath-holding as the vasodilatory stimulus.

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