Open AccessPenumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats.
Author(s) -
Hajime Memezawa,
M L Smith,
Bo K. Siesjö
Publication year - 1992
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.23.4.552
Subject(s) - medicine , middle cerebral artery , occlusion , stroke (engine) , cardiology , ischemia , mechanical engineering , engineering
The rat is now extensively used for studies on focal cerebral ischemia, and several novel pharmacological principles have been worked out in rat models of middle cerebral artery occlusion. The objective of the present study was to assess how ischemic tissue can be salvaged by reperfusion in a model of transient focal ischemia that gives infarction of both the caudoputamen and the neocortex.
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