Glucose-associated alterations in ischemic brain metabolism of neonatal piglets. | Zendy

Abbot R. Laptook | Zendy; Ronald J. T. Corbett | Zendy; Orlando ArencibiaMireles | Zendy; Joan I. Ruley | Zendy

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Glucose-associated alterations in ischemic brain metabolism of neonatal piglets.

Author(s) -

Abbot R. Laptook,

Ronald J. T. Corbett,

Orlando ArencibiaMireles,

Joan I. Ruley

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.10.1504

Subject(s) - medicine , metabolism , ischemic stroke , carbohydrate metabolism , ischemia , endocrinology , physiology

During global brain ischemia or hypoxia-ischemia in adults, hyperglycemia is deleterious to the brain. In contrast, similar adverse effects have not been found in neonatal animals. This investigation examined neonatal piglets to determine if there were specific alterations of ischemic brain metabolism associated with different systemic glucose concentrations and to potentially clarify the effects of hyperglycemia during ischemia in neonates.

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