Protective effects of human recombinant superoxide dismutase on transient ischemic injury of CA1 neurons in gerbils. | Zendy

Osamu Uyama | Zendy; T. Matsuyama | Zendy; H Michishita | Zendy; Hitoshi Nakamura | Zendy; M Sugita | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Protective effects of human recombinant superoxide dismutase on transient ischemic injury of CA1 neurons in gerbils.

Author(s) -

Osamu Uyama,

T. Matsuyama,

H Michishita,

Hitoshi Nakamura,

M Sugita

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.1.75

Subject(s) - superoxide dismutase , dismutase , ischemia , reperfusion injury , medicine , endocrinology , microbiology and biotechnology , biochemistry , oxidative stress , biology

It has been postulated that oxygen-derived free radicals are produced in significant quantities upon reperfusion of ischemic brain and that the free radicals play a pivotal role in triggering the ischemic neuronal damage causing delayed neuronal death. This study was undertaken to examine the effects of human recombinant superoxide dismutase on the delayed neuronal death of CA1 neurons and on the change in the expression of messenger ribonucleic acid for endogenous copper-zinc superoxide dismutase after transient ischemia.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research