Effect of 33% xenon inhalation on whole-brain blood flow and metabolism in awake and fentanyl-anesthetized monkeys. | Zendy

Liping Yao | Zendy; Jesus Bandres | Zendy; Edwin M. Nemoto | Zendy; J.R. Boston | Zendy; Joseph M. Darby | Zendy; Howard Yonas | Zendy

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Effect of 33% xenon inhalation on whole-brain blood flow and metabolism in awake and fentanyl-anesthetized monkeys.

Author(s) -

Liping Yao,

Jesus Bandres,

Edwin M. Nemoto,

J.R. Boston,

Joseph M. Darby,

Howard Yonas

Publication year - 1992

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.23.1.69

Subject(s) - cerebral blood flow , medicine , anesthesia , inhalation , fentanyl , blood flow , oxygen , arterial blood , cardiology , chemistry , organic chemistry

Despite the documented diagnostic value of local cerebral blood flow maps by xenon-enhanced computed tomography, reports of cerebral blood flow activation by inhaled 33% Xe raised concerns about the method's safety and accuracy. We evaluated the effect of 33% Xe inhalation on cerebral blood flow and cerebral metabolic rates for oxygen and glucose in four awake and six fentanyl-anesthetized rhesus monkeys.

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