Global cerebral ischemia in piglets under conditions of mild and deep hypothermia. | Zendy

L. Sutton | Zendy; Bernard J. Clark | Zendy; Carol R. Norwood | Zendy; Edward Woodford | Zendy; Frank A. Welsh | Zendy

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Global cerebral ischemia in piglets under conditions of mild and deep hypothermia.

Author(s) -

L. Sutton,

Bernard J. Clark,

Carol R. Norwood,

Edward Woodford,

Frank A. Welsh

Publication year - 1991

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.22.12.1567

Subject(s) - phosphocreatine , hypothermia , medicine , adenosine triphosphate , ischemia , circulatory system , anesthesia , cardiopulmonary bypass , adenosine , endocrinology , energy metabolism

To investigate the effects of hypothermia on the rate of change and degree of recovery of brain adenosine triphosphate and phosphocreatine concentrations and intracellular pH, we have developed a model that allows phosphorus nuclear magnetic resonance spectroscopy of the intact piglet brain during circulatory arrest.

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