Neurochemical analysis of focal ischemia in rats. | Zendy

Yoshiaki Uemura | Zendy; Joanne M. Miller | Zendy; Wayne R. Matson | Zendy; M. F. Beal | Zendy

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Neurochemical analysis of focal ischemia in rats.

Author(s) -

Yoshiaki Uemura,

Joanne M. Miller,

Wayne R. Matson,

M. F. Beal

Publication year - 1991

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.22.12.1548

Subject(s) - uric acid , ascorbic acid , hypoxanthine , xanthine , neurochemical , xanthine oxidase , glutathione , medicine , ischemia , xanthine dehydrogenase , endocrinology , radical , biochemistry , metabolism , enzyme , chemistry , food science

Increases in uric acid follow experimental stroke, which may be related to free radical formation by xanthine oxidase. The present study examined the time course of changes in xanthine and uric acid and their relationship to changes in the free radical scavengers glutathione, cysteine, and ascorbic acid.

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