Open AccessPlatelets augment rabbit cerebral artery constriction by activating protein kinase C.
Author(s) -
P. Germann,
Ismail Laher,
John A. Bevan
Publication year - 1991
Publication title -
stroke
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.22.12.1532
Subject(s) - thrombin , platelet , medicine , protein kinase c , histamine , endocrinology , endothelium , protein kinase a , staurosporine , kinase , chemistry , biochemistry
We tested the hypothesis that activated platelets augment cerebral artery responsiveness to thrombin by activating protein kinase C, a possible intracellular modulator of Ca2+ sensitivity.
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