Cerebral sinus thrombosis as a potential hazard of antifibrinolytic treatment in menorrhagia. | Zendy

Anat Achiron | Zendy; Michael Gornish | Zendy; E. Melamed | Zendy

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Cerebral sinus thrombosis as a potential hazard of antifibrinolytic treatment in menorrhagia.

Author(s) -

Anat Achiron,

Michael Gornish,

E. Melamed

Publication year - 1990

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.21.5.817

Subject(s) - medicine , antifibrinolytic , superior sagittal sinus , aminocaproic acid , thrombosis , surgery , anesthesia , thrombophilia , tranexamic acid , blood loss

We describe a 42-year-old woman who developed superior sagittal and left transverse sinus thrombosis associated with prolonged epsilon-aminocaproic acid therapy for menorrhagia. This antifibrinolytic agent has been used in women with menorrhagia to promote clotting and reduce blood loss. Although increased risk of thromboembolic disease has been reported during treatment with epsilon-aminocaproic acid, cerebral sinus thrombosis has not been previously described. Careful use of epsilon-aminocaproic acid therapy is recommended.

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