The importance of brain temperature in cerebral ischemic injury.
Author(s) -
Raul Busto,
W. Dalton Dietrich,
M Globus,
M. D. Ginsberg
Publication year - 1989
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.20.8.1113
Subject(s) - medicine , miami , neurology , cerebral blood flow , cerebral autoregulation , anesthesia , blood pressure , autoregulation , psychiatry , environmental science , soil science
Observations of cerebroprotection by hypothermia are not new, though traditional approaches have tended to employ overall reductions of wholebody temperature of rather sizable magnitude. In contrast, our laboratory first suspected several years ago that small fluctuations of brain temperature might account in part for variability in the extent of tissue injury encountered in animal models of reversible ischemia
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