Effect of nitroglycerin on cerebral circulation measured by transcranial Doppler and SPECT. | Zendy

A. Dahl | Zendy; David Russell | Zendy; R Nyberg-Hansen | Zendy; K. Rootwelt | Zendy

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Effect of nitroglycerin on cerebral circulation measured by transcranial Doppler and SPECT.

Author(s) -

A. Dahl,

David Russell,

R Nyberg-Hansen,

K. Rootwelt

Publication year - 1989

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.20.12.1733

Subject(s) - medicine , transcranial doppler , cerebral blood flow , cerebral circulation , middle cerebral artery , nitroglycerin (drug) , vasodilation , cerebral perfusion pressure , blood flow , perfusion , anesthesia , perfusion scanning , cerebral arteries , cardiology , ischemia

We used a combination of transcranial Doppler ultrasonography and single-photon emission computed tomography to noninvasively assess changes in the diameter of the middle cerebral artery induced by sublingual nitroglycerin in 10 healthy subjects. Nitroglycerin reduced mean blood flow velocities without concurrently changing regional cerebral blood flow in the perfusion territory of this vessel. Our results strongly suggest that nitroglycerin causes vasodilatation of the basal intracranial arteries.

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