Altered leukocyte rheology in patients with chronic cerebrovascular disease. | Zendy

I. Vermes | Zendy; F. Strik | Zendy

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Altered leukocyte rheology in patients with chronic cerebrovascular disease.

Author(s) -

I. Vermes,

F. Strik

Publication year - 1988

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.19.5.631

Subject(s) - medicine , clogging , concomitant , disease , cardiology , filtration (mathematics) , statistics , mathematics , archaeology , history

Erythrocyte and leukocyte suspensions were prepared from 28 patients with chronic cerebrovascular disease and 30 age- and concomitant disease-matched control subjects. Cell filterability was studied with the new St. George's filtrometer, which can discriminate between initial filtration rate as an erythrocyte parameter and filter clogging as a leukocyte parameter. Compared with control subjects, a significant increase of filter clogging was found in the patients, suggesting decreased deformability or increased adhesiveness of leukocytes or both in chronic cerebrovascular disease.

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