Ischemic stroke associated with anticardiolipin antibodies. | Zendy

Steven R. Levine | Zendy; S. Kim | Zendy; M. J. Deegan | Zendy; K.M.A. Welch | Zendy

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Ischemic stroke associated with anticardiolipin antibodies.

Author(s) -

Steven R. Levine,

S. Kim,

M. J. Deegan,

K.M.A. Welch

Publication year - 1987

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.18.6.1101

Subject(s) - medicine , lupus anticoagulant , anticardiolipin antibodies , autoantibody , stroke (engine) , systemic lupus erythematosus , antibody , cerebral infarction , antiphospholipid syndrome , immunology , systemic disease , ischemic stroke , anticoagulant , connective tissue disease , autoimmune disease , immunopathology , disease , ischemia , mechanical engineering , engineering

Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke.

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