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Frequency of cerebral infarction in patients with inherited neuromuscular diseases.
Author(s) -
José Biller,
Victor Ionâşescu,
H Zellweger,
Harold P. Adams,
Douglas Schultz
Publication year - 1987
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.18.4.805
Subject(s) - medicine , myotonic dystrophy , cardiology , atrial fibrillation , muscular dystrophy , ataxia , cerebral infarction , infarction , atrial flutter , fibrillation , myocardial infarction , ischemia , psychiatry
We evaluated the frequency of cerebral infarction in 131 patients with Duchenne's muscular dystrophy, myotonic dystrophy, Becker's muscular dystrophy, or Friedreich's ataxia. Electrocardiographic abnormalities were found in 83% of patients with Duchenne's muscular dystrophy, 56% with myotonic dystrophy, 50% with Becker's muscular dystrophy, and 25% with Friedreich's ataxia. Atrial flutter occurred in 2.3% of the patients, and atrial fibrillation in only 0.9%. Evidence of cerebral infarction was found in only 2 patients (1.5%). Both patients had cardiomyopathy and either atrial fibrillation or flutter. Despite frequent cardiac involvement, cerebral infarction is an uncommon occurrence in patients with inherited neuromuscular diseases.

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