Cerebral venous thrombosis with lupus anticoagulants. Report of two cases. | Zendy

Steven R. Levine | Zendy; Stuart N. Kieran | Zendy; K Puzio | Zendy; HERMANN FEIT | Zendy; Suresh Patel | Zendy; K.M.A. Welch | Zendy

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Cerebral venous thrombosis with lupus anticoagulants. Report of two cases.

Author(s) -

Steven R. Levine,

Stuart N. Kieran,

K Puzio,

HERMANN FEIT,

Suresh Patel,

K.M.A. Welch

Publication year - 1987

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.18.4.801

Subject(s) - medicine , venous thrombosis , lupus anticoagulant , partial thromboplastin time , thrombosis , stroke (engine) , intracranial thrombosis , anticoagulant , cardiology , platelet , mechanical engineering , engineering

Lupus anticoagulants are circulating autoantibodies, primarily directed against phospholipids, that prolong the partial thromboplastin time. They have been previously associated with systemic arterial and venous thrombosis and arterial stroke, but not with cerebral venous thrombosis. We describe 2 young patients with cerebral venous thrombosis documented by intravenous digital subtraction angiography in whom a lupus anticoagulant was demonstrated. Both patients improved with corticosteroid and anticoagulant therapy.

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